Seprion™

The Seprion™ range of products detect aggregated proteins associated with a wide range of diseases. This includes Parkinson’s, Alzheimer’s, Huntington’s diseases, and the Transmissible Spongiform Encephalopathies such as BSE, scrapie, vCJD and CWD.

• Suitable for a variety of diseases
• Convenient and flexible format
• Easy to interpret

We have commercialised our Seprion™ BSE product, with a US partner, and this dominates the worldwide market for prion disease testing.

For diagnosis, detection and research studies it is very difficult to differentiate the abnormal aggregated form of the proteins from the normal unaggregated form. To address this problem, we have developed polymeric ligands (our Seprion™ range) which only bind to the abnormal or altered aggregated form of the protein.

The Seprion™ ligands have been proven to bind abnormal prion, β-amyloid, α-synuclein, tau, huntingtin and aggregated p53 in cancer cells.

They can also be used to monitor the aggregation state of manufactured therapeutic proteins such as antibodies.

Our Seprion™ ligands are supplied coated onto magnetic beads or onto 96-well microplates which gives the researcher the flexibility of separation and assay format.

 

To get in touch with one of our team, call +44 (0)20 76912147 or email patrick.breen@microsensdx.com

 

 

Our products

RapiPREP®

The most accurate and sensitive SARS-CoV-2 tests, Loop-mediated Isothermal Amplification (LAMP) and, polymerase chain reaction (PCR), both require RNA to be extracted from a patient’s sample before it can be amplified and analysed.

RapiPRO™

Loop-mediated Isothermal Amplification (LAMP) is a method of nucleic amplification which has grown in popularity thanks to its speed, efficiency, and low cost when compared to PCR testing.